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Yu tu gang12/10/2023 JAMA 2018 320:2564-79.The Apparition Gang was the Younger Toguro and Elder Toguro's gang of demon mercenaries. Association of pharmacological treatments with long-term pain control in patients with knee osteoarthritis: a systematic review and meta-analysis. Gregori D, Giacovelli G, Minto C, Barbetta B, Gualtieri F, Azzolina D, et al. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Semin Arthritis Rheum 2013 43:303-13.ĭa Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, Jüni P, et al. Health economics in the field of osteoarthritis: an expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Hiligsmann M, Cooper C, Arden N, Boers M, Branco JC, Brandi ML, et al. Knee osteoarthritis has doubled in prevalence since the mid-20th century. ![]() ![]() Wallace IJ, Worthington S, Felson DT, Jurmain RD, Wren KT, Maijanen H, et al. © 2020, American College of Rheumatology. Intensive MA had no benefit for knee OA at week 8, although it showed benefits during follow-up. The response rates in the EA and MA groups were both significantly higher than those in the SA group at weeks 16 and 26.Īmong patients with knee OA, intensive EA resulted in less pain and better function at week 8, compared with SA, and these effects persisted though week 26. Of the 480 participants recruited in the trial, 442 were evaluated for efficacy. The primary analysis was conducted using a Z test for proportions in the modified intent-to-treat population, which included all randomized participants who had ≥1 post-baseline measurement. The primary outcome measure was response rate, which is the proportion of participants who simultaneously achieved minimal clinically important improvement in pain and function by week 8. Participants, outcome assessors, and statisticians were blinded with regard to treatment group assignment. In this multicenter, randomized, sham-controlled trial, patients with knee OA were randomly assigned to receive electroacupuncture (EA), manual acupuncture (MA), or sham acupuncture (SA) 3 times weekly for 8 weeks. To assess the efficacy of intensive acupuncture (3 times weekly for 8 weeks) versus sham acupuncture for knee osteoarthritis (OA).
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